22:00 GMT+0 is the Forex daily close & re-open time. Please take note, this is the time which the market will become volatile. Spreads will enlarge and the liquidity is thinner than usual and this may lead to larger slippage, partial fill or even reject.
The same situation applies to Friday market close and on Sunday market open or when big news is released. Forex/CFDs are high leveraged trading products, we would highly recommend you to pay more attention to your account positions and make sure you have sufficient funds in your account.